Leaving aside the benefits of cropping on a full-frame camera as mentioned by others, you might want to consider the revised "Bigma" instead of the 150-500. I was all set to buy a 100-400L, but something made me consider the Sigma 50-500 and after reading more than a few favorable reviews and discussions of it online (which suggest/show that it beats their 150-500 and 120-400) I rented one from lensrentals a couple of weeks ago and liked it enough to buy one (in lensrentals' Black Friday sale, luckily). It took me a while to get used to the weight, but I was pleasantly surprised by how good the OS is (avoid the previous version, which, among other drawbacks, has no stabilization at all) and, even more, by the precision of its focusing - on objects both close and far. It's not the last word in sharpness, but you wouldn't expect that in a 50-500 lens and I think it compares well to the Canon 100-400 in that regard (and, unless there was something wrong with the 100-400 I rented, beats the Canon handily in terms of bokeh; better image stabilization too, as you might expect from a much more recent lens). So you may want to try one yourself and see what you think.