So, a bit of math.
w/o IS: 1/60s @ f/1.4 @ ISO 6400 = EV 1 => "Distant view of lighted skyline."
w/ IS: 1/4s @ f/1.4 @ ISO 6400 = EV -3 => "Night, away from city lights, subject under full moon."
@ ISO 25,600 = EV -5 => "Night, away from city lights, subject under crescent moon."
1/2s @ f/1.4 @ ISO 25,600 = EV -6 => "Night, away from city lights, subject under starlight only."
So, yes. With this, if you braced yourself well, you actually could take a handheld landscape picture of the Grand Canyon at midnight on a clear moonless night and have it be as well exposed as one under the noonday Sun. It'll be a bit noisy if you pixel peep, but an 8" x 10" print will be stunning. Indeed, you might even wind up overexposing the Milky Way if you're not careful!
(And, of course, you'll need not have anything in the foreground due to the shallow depth of field.)