And-Rew:
Thanks for bringing this thread back on track by contributing the first on-topic post since a few days...

Actually after (shortly) trying out the similar sized Sigma 500 this week I'm completely with you on the weight issue. Its far less than I expected at the beginning. Absolutely no problem to carry around in a backpack (that brings the weight to the hips) and probably no problem to carry in my hands for extended periods of time. Holding it to eye-level without support will still be a different story. But I'm sure I can find something to rest my arms on.
It's very common to take a spill on a bike, and just one would wreck that lens.
I had two accidents in the last three years (since I'm going by bike regularly) - both within the same week. It was wet, there were some leafs on the ground, I was going too fast... you know the story.

I don't make those mistakes when carrying expensive gear so it's not very common to take a spill for me, plus canon claims that the V2 has "twice the impact resistance" than the V1. Of course I could get hit by a car - but my gear wouldn't be my first concern then.
Rat: Thanks for the hint but the weight will be no problem for my bike.
Man up and buy it ffs.
Couldn't you have told me this right at the beginning - then we could have spared ourselves the trouble of this huge thread...

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At the moment I clearly tend to the buying side. I will not get it before April though, so I have still some time to think about it.