My "favorites" in my collection right now:
*F-stop LOKA used when trekking with a camera. Comfortable and holds a lot besides just my photo gear.
*KATA All-in-one. Great if you want a sling type bag but beware, no sling is really comfortable with a lot of weight and converting this to a two-shouldered backpack reveals its comfort limitations as a backpack.
*Thinktank Retrospective. This is, without a doubt, the most practical and functional shoulder pack I've ever cried. The strap might be the most comfortable I've ever had over my shoulder. I've got the Retro-7 and can carry a 5Diii, 24-105, 17-40, shorty 40, memory, batteries and a notebook (the paper kind....not the electronic kind) for hours.
That being said, of the two you are looking at, I'd bet the KATA is more comfortable. If you can, go somewhere and play with these bags before buying.
I like the f-stop bags—especially love the Millar series shoulder bag, even though they don't fit much. Might consider one of those down the line.
Unfortunately there is only one [decent] local camera shop, and their stock isn't great. Of the few things they sell that I would buy, it's way overpriced compared to what can be found online so I've never bought anything. They don't carry any L lenses other than 70-200 f4s and 17-40s... Maybe they have a hidden stash, but I havent had a reason to ask yet.... Most of their bags are lowepros. They DID have one Kata 222 "PL", which is similar to the 111 but bigger and heavier, and the inside is completely dedicated to gear (not divided off on top, and no aluminum frame like the UL versions). It WAS comfortable though. I liked the "gecko" straps and the overall feel. And sitting next to a bunch of lowepros and other brands I didn't recognize—it looked more well made.
Also, @fugu82, I wasnt a fan of the bottom opening part. And I don't have 6 men and a boy to help me out lol. Might be a good excuse to find 6 women and a... another woman to help me out. LOL
The Think Tanks are pretty popular it seems. I'm seeing the name everywhere when I search for bags online... one thing I find funny is that, for a brand that seems to target a crowd who wants an inconspicuous bag, they chose a logo that looks extremely similar to one of the most widely known tech brands.... Thinkpad. Just an observation... because I know they don't really stamp it all over their bags (like lowepro likes to do...)