I Love my ThinkTank Airport Takeoff (http://www.thinktankphoto.com/products/airport-takeoff-roller-camera-bag.aspx
)- Perfect for me-size, weight, fits in even small planes, holds two bodies with lots of lenses, flashes, and stuff.
Just got the Airport International Security 2. It is larger, and heavier. It feels much heavier/larger than it is, and holds tons of stuff. Haven't taken it out yet.
Bags are of excellent construction-ballistic nylon, adjustable innards. Not too many or too few compartments, and good protection of gear. Tripods secured on the side so it has smaller profile to fit in overheads better, but less balanced for carrying.
Overall, what I love about the roller bags is that the gear is heavy, and once you get used to getting the load off your back, you learn to love pulling it. The wheels just glide nicely. Don't pull them in the dirt as that will soil the bearings.
One last thing, they have a compartment for at least a 15" lappy.
Very durable, I expect it to last longer than I do.
I only wish that the handle was spring loaded to pop out like Lowepro, which I think has a larger profile.