I have 2 places for my "Good Gear" that I use a lot. The old crappy lenses and stuff I don't care about just sit in cupboard in the garage.
I am paranoid since I have had camera stuff stolen before on a filming trip in Peru.
1) I have a large Gun Safe (I don't own any guns), but this is where I keep my Large-ish LowePro backpack with all of the essential lenses the body for a shoot. I have a second small LowePro backpack that I keep in the safe to hold overflow. Both bags have a number of silica lyca gels inside to keep them dry. I always have my lenses face down because I have a UV filter on all the lenses and if I forget the cap, the UV filter is taking the hit, and not the rear element glass. Having everything in a backpack is nice because it's super organized and I can just grab it on the fly.
2) I have a locked closet (crappy lock though) where I keep all my grip gear -- stands, rigs, lights, etc..
I have everything about 1 foot off the ground in case of flooding. At least all the electronic stuff.
This reminds me, I need to re-insure my stuff. Very important as someone who has had stuff stolen.
Oh yes, I usually keep all my grip gear and lights in separate various bags, well organized. I have a ton of crap, but everything is inside about 7 bags so I can just quickly pack the bags in my car and be off.
I'm pretty messy and unorganized when it comes to life and my house. But with my camera gear, my film projects and computer files, I am super organized and methodical. You have to be or else you'll just lose stuff.