If the 5D2 had a good AF system and a much better native ISO range (e.g. 100-12,800 as with the D3s). Then no. The 5D2 is currently selling for 2k in Toronto. Great deal. But since it has questionable AF speed (or so I've heard) and is not known for shooting in low-light...I'm hoping Canon will make those two changes in the 5D3.
Nope, 5D2 does not have questionable AF speed, nor does it have a problem focusing in low light - as long as you only focus using the centre AF point.
And there is its achilles heel - only 1 decent AF point, only 9 in total - only the centre point is a cross type AF sensor.
AI Servo is ok so long as you're not tracking a hare running from a fox! Oh, and only using centre AF point!
As for native ISO - have tested mine side by side with a D3s - and the Nikon shooter (who loves to mock Canon at every opportunity) conceded that actually the 5D2 handled itself well up to the 12800 point. Not quite up with the D3s, but not enough to justify the extra cost or switching.
I personally run with 6400 without a second thought, and have been known on many an occasion to shoot at 12800 and 25600, letting LR3 manage the noise to an acceptable level.
As some one who happily pushed film to ASA 12800, i've often wondered just what people expect from a shot at 12800? Or maybe they're just people who have never seen how grainy a picture is taken at ASA 12800? On a par, i would say the 5D2 would have to have an H3 setting to 51k to get the equivelant noise/ grain, maybe even an H4 to 102k. The 1Dx at 204k seems to give noise/ grain at no more than i got from 3200ASA pushed 1 stop...