I just checked my new 5D MK III body for sharpness. I removed most variables by tethering it to my pc and shooting carefully exposed images with my macro lens, They are all razor sharp with the sharpness slider at zero and no NR. Then I used the advanced release of Adobe DNG converter. I couldn't ask for better.
Now that I've established that the body takes razor sharp images, I'll want to AFMA all my lenses (14 + 2TC), but that is a painstaking job, and I'd prefer to wait until FoCal gets updated if I can. From what I see, most of the lenses are very good, but not perfect at autofocus accuracy. Each body is slightly different.
I may just adjust the most commonly used ones for now.