I have & use the 5DMK2, 1DMK4 & now the 5DMK3, in General terms the 5DMK3 is the clear winner, Picture quality no better than the MK2 (but marginally better than the 1DMK4), but everything else, in particular the Auto Focus system on the newer 5DMK3 is wonderful. The areas that the 1DMK4 outdo the 5D's is in the APSH sensor, for those shots on a Telephoto where i don't quite have the Legs, the 1.3 Crop often gives me the edge i need, also in all round weather/dust proofing the 1 Series walk all over the 5D's although i understand the MK3 is improved, time will tell. But if your looking for a great semi pro camera, the 5DMK3 is it, off course it would have been nicer if it could have been delivered without the issues, light leaking top LCD, my 200 f/2 Lens locks up on the IS when attached to the MK3, Software doesn't allow RAW processing on the MK3, Once Canon wake up & solve these issues, which they will, this will be a great addition to anyones Photographic endevours.