Almost exclusively manual. If it's in nighttime I fix the ISO rather high and leave it. If it's daytime I often set it to auto-ISO. In both cases manually controlling aperture and shutter. I don't like aperture priority, it often sets shutter speeds that aren't hand-holdable in darker conditions. Shutter priority doesn't have such a dilemma but still leaves you without control over DOF. For the night-time shots where I fix the ISO high, unless I would be going for an effect, I just alter the shutter to control exposure, and only change the aperture if I want to change the DOF, it's fairly simple. Custom modes are quite useful if you are at an event, it lets you preset a few various styles or quickly account for stark differences in lighting you may find. I'm gradually getting used to manual focusing as when I don't completely miss, it leads to much better images than the tack sharp mechanical results which gets quite boring after a short while.