Get Photoshop CS6, it gives you a lot more options than LR4, plus for 'batch' processing or using scripts it is incredibly useful. You can record and save your actions as a new action set (e.g. process one photo) then use a script to perform similar actions on a large number of other pictures taken at the same time and place.
I use Nik Software Suite, especially the Sharpener Pro 3.0 and it is very good for fixing localized areas (e.g. peoples faces or specific objects in frame), but it can be time consuming i.e. setting multiple control points etc., but on the plus side it is very quick to process, menu intuitive, user friendly and so on. It is a great tool for adjusting either contrast, focus, or sharpness in a designated part of the composition. Have never used the RAW Pre-Sharpener, but I imagine it is just as good. Quite extraordinary, some of the results - really makes faces pop-out.