I think we will not see any radical departures in form from the current body.
1Dx mk. IV will:
1. Have a mirrorless mode where a translucent mirror can be latched in for faster FPS’s or keep it in the Mirror mode. Either this or it becomes completely Mirrorless with EVF.
2. 40-60mp seems a lot, but if there is a higher MP version of the 1D, then this would be the target range. They will try and kill the MF format if they can with better sensors.
3. Touch screen functionality will be mature and you will be able to tether your iphone 12 / Galaxy S14 for tethered shooting. The apps will allow for Focus bracketing and other timelapse fun. Canon will actually have SDK for it

4. New Sensor tech will allow for 2-3 stops of ISO improvements in RAW and 8-10 stops in jpeg
5. Even Canon will have +14 DR :-)
6. Multiple crop modes will be available for a given sensor/ this will include the ability to choose what binning ratios to use in case of simple down sampling of non-crop modes.
7. Bye Bye Bayer, Bye Bye MOIRE,
8. As mentioned Lens modeling and sensor diffraction/ resolution bottlenecks will be aligned.
9. I do not think the manufacturing of glass will be so good that we will see zero sharpness gained by stopping it down, I think that will not happen in 10 years… maybe 20-25.
10. Focussing by eye should become standard unless everyone used the Lytro style Field vision sensors.
11. RGB metering will be available in cell phones… so DSLR’s will get much better exposure meters.
12. Lenses and apertures will have reflective coatings to increase photon concentration on the sensor for high ISO requirements at the cost of some IQ offsets.
13. Polycarbonate elements will be good enough to be used in lenses drastically lowering the prices of EF lenses. This I see happening in more than 10 yrs. The lenses might require a mandatory UV filter to protect against scrapes etc.
14. Via Geo Tagging, the camera will be able to remember the last time you were in a certain place and suggest starter settings based on the last time you shot there e.g. Sports arena vs. Studio shoot.
15. By pointing on an object (skater/insect/wildlife/child/model) on the touchscreen on the Camera, it will recognize what it is your are trying to shoot and once confirmed, the AF will constantly track the subject even faster than your eyeballs can lock on to it.