The 1Ds3 has a setting in C.Fn whereby the lens is first in Manual focus, then you can choose an option to, after taking the first picture, allow AF capabilities. This would be useful for images where the subject is difficult for the AF to find, but once it does, it stays locked on. If that is set, it will not AF on shot 1, but then you can do it for subsequent shots. On the 5D Mark III I cannot locate such a function/capability.