Some general regional language tips as far as I can tell:
English is usually spoken by many locals in Northern and Central Europe, less so in Italy and France or Russia. Especially in Russia you better speak Russian or get an interpreter.
For whatever reason Italians often speak French as a preferred second language, less often English. If you know some Spanish or Portuguese or French, you should be able to make do, if perhaps only in a special way: Speaking to others without any problems despite not understanding each other's languages. If anyone, then Italians are perfectly capable of that.
Disclaimer: Please be aware that personal findings may differ wildly from the statements provided here. This is just my personal view and I had to resort to some generalization, which is always problematic.