Not bad, but the eyes look like they don't belong in that face. A big part of it is not just the selective color processing but also that they're the only things that're sharp due to the shallow depth of field. I'd like to have seen the shot stopped down a bit more, at least enough to have the whole forehead sharp. Really, this particular shot would have been perfect for f/8 - f/11 so you could be hit by the full impact of all the grittiness rather than have some or much of it safely softened and eased out of your mind. I'd even have done so if it meant boosting the ISO -- grain would help, not hurt, this picture.
Just because you can shoot wide-open at a low ISO with only a sliver of the frame in sharp focus doesn't necessarily mean you should....