What we can expect over the next year or so is a deluge of HSS enabled monolights flooding out of China. What's more they'll likely have TTL as well. The era of dependable "dumb" studio packs and monos is now pretty well consigned to history. This is fun.
What exactly do you think has changed. These "Dumb" studio packs already shoot at 1/8000 of a second, and it is the trigger and remote that makes a difference.
While my photogenic monolights were not the best, I actually went from monolights to studio packs because I find the quality of the Dynalite is better as well as it is easier to transport. The cables can sometimes be a pain, but in general it is easier to put a flash head 15 feet in the air on a stand and not worry than a most monolights. My case with 2000 watt pack, and 4 heads takes a lot less space than the huge Pelican 1650 I carried 3 Photogenic modeling lights in. In fact my Dynalite case I can carry a 1000 watt pack, 500 watt pack, photogenic Ion battery and 3 heads and it is close to half the size of what I carried the photogenics. The Alien Bees and Einsteins are smaller, but there are always trade offs.
Recycle time is also much faster
The Einsteins are an anomaly and probably the best bang for the buck out there. They have decent power, but also one of the shorter flash durations.
When it comes to High Speed Sync and Hyper Sync, the Quality of light, power of light and duration of light matter. In short you need to throw a ton of power out over a very short period of time. In many cases it is probably cheaper to throw high powered constant lights and freeze everything with shutter.
Some of the Dynalite packs I use are 10+ years old... I still shoot them plus side of 1/2000, I can go to 1/8000 but I find the flash duration makes a difference, and the more you really start shooting HSS you notice variations. Whether you do Odin, PocketWizard or a few others, the trigger is the magic in HSS not the strobe. And as mentioned try synching a second remote camera into the mix and you see how much Odins or PocketWizards come into play.
Regarding Monolights / packs / speedlites - Speedlites are still the most convenient in the field, though power and recycle become an inssue. I found a healty balance with my Dynalite and found 2 or 3 heads off a Dynalite pack on a Photogenic Ion worked much better than multiple monolights on the same Ion, mainly the more monolights you throw into the mix, the more capacitors that have to be reloaded each flash.
Your point on TTL is coming from what??
TTL is camera based, so a Canon TTL is different than a Nikon TTL etc. Speedlites are already manufacturer dependent, and I cannot see MONOLIGHTS being the same.
This is why you have packs, packs use their own or third party triggers, and that way, you want to shoot canon, Nikon, Hassleblad, Sony, what ever, it is more letting the manufacturer or third party system worry about it.