6D 24-105 @ 40mm f/11 @ 1/60 ISO 400:
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I have no hesitation using my 6D up to ISO 25,600, If you have a properly exposed photo, noise is perfectly acceptable at high ISO.
Third party "digital" lenses are not the same thing as EF-S lenses, if you want to butcher the safety stops then some EF-S lenses can be used to take
crapheavily vignetted images on a ff camera with the risk of severe damage to that camera, hardly seems worth the effort.
I do remember back in the day people did experiment with the practicality of various EF-S lenses on EF mounts, mainly so they could use EF-S lenses on the 10D as that predated EF-S and was EF only.