I'm very used to canon controls, so I used the custom key settings to replicate. The control wheel is aperture and the front dial is shutter speed, for example. I have the center button set to AF on, with focus on the shutter release disabled. C2 toggles metering mode. C1 magnifies manual focus. C4 (I think) is set to eyeAF (only works with native lenses). Down brings up AF mode (don't recall the name of the function), from which I select AF point.
And I loaded up the Fn menus with other common stuff. I basically don't have to access the menus for much of anything.