CTJohn said:
Non-techie here. Can you explain that? I've been using my 6D with an ISO limit of 6400 and pretty happy with the results. Are you saying I would get better results limiting at 3200 and bumping exposure in Lightroom?
Not unless you're needing the bit of dynamic range you're loosing on iso3200->6400. Canon does a very good job at 6400 on the 6d, I use it myself when in a pinch - but when in doubt don't hesitate to simply underexpose 3200. But everything >6400 is simply a waste if you're shooting raw stills.
More tech explanations can be found in the Magic Lantern forum, they discovered this when developing their mini_iso module that tweaks the various amplifier stages of the image processing chain.
Sabaki said:
What does ISO 50 bring to the table and as per your comments, is it analogue?
No, iso 50 (for the cameras that have it, i.e. not 6d) is simply iso 100 overexposed - check the dynamic range curve, magically iso 50 has one stop less than iso 100

. Iso 50 is very useful though for fast lenses because you don't need to use a nd filter if your shutter speed is maxed out.
Sabaki said:
Tell me more about the penalties of using "non analogue" ISO please?
If you're digitial iso, you're simply under/overexposing in-camera. The result is that the histogram only gets shifted left or right, and the side part gets chopped off (i.e. you're loosing dynamic range). The noise level & color fidelity is the same as the base "analog" iso that's actually set on the sensor.
Intermediate iso steps are nice for video, jpeg, timelapses, whatever - but not for shooting raw stills, in the best case you're gaining nothing, in the worst case you're throwing away image data.