I've not tried the new 70-200/2.8 Z, but I am very familiar with the older EF 70-200/2.8 II counterpart. It was an astonishingly sharp lens even with a 1.4x tc. It af our resolves any of the current Canon sensors. The 2x less so, still sharp but want's great with close objects and generally needed stopping down 2/3 stop to remove the slight haze around highlights. The thing is, a pair of teleconverters is a lot lighter than lugging around another sized lens. Even the 2x TC works well if that's the only thing you have on you. I appreciate that this new RF Z version is a tad sharper again, but it's still in the same ball park with teleconverters.
The RF 70-200/2.8 is a miracle in packaging and light weight construction by comparison, but we all know of the lack of TC support for this sweet lens.
The RF 100-300mm f2.8 is a very different beast. With tele converters, it's pushing into wildlife and birding reaches. Even with a 2x TC (making a 600mm f5.6) it just about keeps up with the R5's resolution of it's mighty sensor. It's a very viable and versatile lens range (100-300/f2.8 > 140-420/f4>200-600/f5.6) and it only cost you the size and weight of a pair of teleconverters. It's never going to compete directly with a 70-200mm f2.8 even though it's got a fair amount of overlap in the focal range and aperture. The Rf 100-300/2.8 is kind of a bridge lens between the 70-200/2.8 and the longer wild life lenses.
I have a few friends who regaulrly use a EF300mm f2.8 II LIS with a pair of teleconverters as their long lens of choice. It's a back friendly size and weight with a nice price point with an excellent reach / brightness. One of them is considering swapping over to the RF 100-300/2.8 so they can ditch the need fro their EF 70-200/2.8 lens and just use the one lens. If Canon made a RF 400-600 f2.8 - F4 zoom lens that's a simular weight to my EF 400mm f2.8 II L and it's as sharp, then my ears might prick up and colour me curious.
I can't imagine the pricetag on a 400-600 f/2.8-4.0 being less than $15-20k, so about twice as much as I'm willing to put down lol

. But certainly that would be a feat of engineering. Like I mentioned a bit earlier, if Canon can churn out longer zooms like the 70-200Z, then they will be very compelling at least for those who can afford any given offering.
Regarding the 100-300L, I'd take one any day if the stork came and dropped it off

. Certainly an outstanding lens. The 70-200Z definitely handles the 2x teleconverter better though:
https://www.the-digital-picture.com...eraComp=1508&SampleComp=0&FLIComp=5&APIComp=0.
There's a reason The Digital Picture called the 70-200Z the sharpest interchangeable zoom they've ever tested! Its teleconverter performance is extremely good. Of course, 400mm is a somewhat limited reach, we can't have everything.
In the comparison with the EF 70-200 f/2.8 L II, it's really not even close though in the images available at 400mm, the old design and teleconverters don't keep up with newer glass:
https://www.the-digital-picture.com...meraComp=979&SampleComp=0&FLIComp=5&APIComp=0. I have an old EF 200mm f/2.8 L (maybe an L II?) and 2x III teleconverter, and the 70-200Z at 400mm is far better than the old prime with an old 2x.
Got some fun shots of this Egret on Saturday with the 70-200Z + 2x (and R5II):
