My 6D2 should last me for probably as many years as I have left, and I don't miss anything it doesn't do. If the 5D V came out, I probably wouldn't buy it. I was tempted to get a 5D IV when it was on sale a few months ago. If it had a flippy screen, I would have ordered it with no hesitation. If I get one, I will still use the 6D2 when I want to use that feature, but use the 5D IV almost all the time when I want to use the OVF. If I'm solvent when they have another sale I'll probably want to get one while I can.
I did consider getting an M50 when I was getting a new travel camera, but chose to go with the G5X II instead, based on my good experience with the G7X II and its pocket size. It has a popup EVF for when it is too bright out to use the screen. That's as close as I have come, or am likely to come, to getting a mirrorless camera with interchangeable lenses. The fast lens on the G5X II has enough focal length range for my travel pictures, except occasionally on the wide end. If I am in close quarters in an interior or am shooting a vast vista and need something wider than its 24mm equivalent, I'll do some shots to make a panorama in Photoshop.